Biology of phosphatidylserine (PS): basic physiology and implications in immunology, infectious disease, and cancer

Abstract Phosphatidylserine (PS) is an anionic phospholipid found on the membranes of a variety of organelles throughout the cell, most notably the plasma membrane.Under homeostatic conditions, PS is typically restricted to the inner leaflet of the plasma HIMALAYAN SALT FINE membrane.However, during cellular activation and/or induction of cell deat

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Rewired Metabolism Caused by the Oncogenic Deregulation of MYC as an Attractive Therapeutic Target in Cancers

MYC is one of the most deregulated oncogenes on multiple levels in cancer.As a In Ground Product (Automation) node transcription factor, MYC plays a diverse regulatory role in many cellular processes, including cell cycle and metabolism, both in physiological and pathological conditions.The relentless growth and proliferation of tumor cells lead to

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Concurrent transcranial magnetic stimulation and electroencephalography measures are associated with antidepressant response from rTMS treatment for depression

Background: Response rates to repetitive transcranial magnetic stimulation (rTMS) for depression are 25-45%.Participant features obtained prior to treatment that are associated with response to rTMS may be clinically useful.TMS-evoked neural activity recorded via electroencephalography (EEG) prior to treatment may be associated with treatment respo

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